Early endosome antigen 1
WebEEA1, early endosome antigen 1 Vertebrate Orthologs 3 Vertebrate Orthology Source. Alliance of Genome Resources. Human Ortholog EEA1, early endosome antigen 1. … Web3 hours ago · Our studies found that CRB3 could colocalize with EEA1-positive early endosomes, CD63-positive late endosomes and Rab11-positive recycling endosomes . In addition, after 2 hours of ... sequentially. Then, antigen retrieval was performed in Tris-EDTA buffer (pH 9.0) heated to 95°C for 20 min. Endogenous peroxidase activity was …
Early endosome antigen 1
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WebThe FYVE domain of early endosome antigen 1 is required for both phosphatidylinositol 3-phosphate and Rab5 binding. Critical role of this dual interaction for endosomal localization. Lawe DC, Patki V, Heller-Harrison … WebAutoantibodies to EEA1, an antigen on early endosomes, were first reported in the serum of a patient with subacute cutaneous lupus erythematosus (SCLE). Here we have …
WebEEA1 Antibodies. Antibodies that detect EEA1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, … WebOct 1, 2013 · Early endosome antigen 1 (EEA1) is a peripheral membrane protein present in cytosol and membrane fractions. Immunofluorescence staining of EEA1 in macrophage cells yields punctuate staining pattern consistent with the cytoplasmic distribution of endosomes, but in a different way when compare uninfected-macrophages ( Fig. 2A ) in …
WebCatalog FieldsAntigen: EEA1; Early endosome antigen 1Available to For-Profits: YesAntigen Species: HumanHybridoma Cells Available (Non-Profit): YesIsotype: … WebSep 16, 2016 · Popular answers (1) The original characterization of "Early Endosomes" is defined by those compartments labeled by transferrin after 20 to 30 minutes of addition. EEA1 (early endosome antigen 1 ...
WebJun 2, 1995 · Early endosomes are cellular compartments receiving endocytosed material and sorting them for vesicular transport to late endosomes and lysosomes or for …
WebRab22a is an important small GTPase protein the molecule that is involved in intracellular transportation and regulation of proteins. It also plays an important role in antigens uptake, transportation, regulation of endosome morphology, and also regulates the transport of antigens to MHC (Major Histocompatibility Complex) molecules. To investigate the role … forme plasticheThe gene EEA1 encodes for the 1400 amino acid protein, Early Endosome Antigen 1. EEA1 localizes exclusively to early endosomes and has an important role in endosomal trafficking. EEA1 binds directly to the phospholipid phosphatidylinositol 3-phosphate through its C-terminal FYVE domain and forms a homodimer … See more EEA1 is a RAB5A effector protein which binds via an N-terminal zinc finger domain and is required for fusion of early and late endosomes and for sorting at the early endosome level. See more Due to the proteins importance in vesicular trafficking, a number of intracellular bacteria prevent EEA1 recruitment to the vacuole. Mycobacterium tuberculosis is known to inhibit the … See more • early+endosome+antigen+1 at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • Overview of all the structural … See more • endosome • Phosphatidylinositol 3-phosphate • FYVE domain See more different pattern in pythonWebSep 27, 2016 · Sequence analysis predicted that the 1,411-amino acid EEA1 protein is largely hydrophilic with short amphiphilic regions in the 15 N-terminal amino acids and in segments centered around amino acids 515 and 645. EEA1 contains an N-terminal zinc finger motif, a cys-rich C-terminal metal-binding finger, and multiple sites for N … forme plastronWebEarly Endosome Antigen 1 Studies of EEA1 have been instrumental in defining the localization of PI(3)P. Closer examination of the protein reveals it is a large coiled-coil protein (Figure 138.3a) that can bind to the GTP-bound form of Rab5, a GTPase required for endosomal membrane fusion [17]. forme power bra reviewsWebNov 28, 2024 · c Statins counter Mycobacterium tuberculosis-induced phagosome arrest by inducing the expression of early endosome antigen 1 (EEA1), which might be due to increased Ca 2+ levels in macrophages. forme plasticaWebJan 17, 2024 · the activation-induced degranulation of Fas ligand has distinct requirements and involves different mechanisms than those of the granule markers CD63 and CD107a/Lamp-1; F. tularensis-containing endosomes associated with early endosome antigen 1 (EEA1) followed by lysosome-associated membrane protein 1 (LAMP-1), with … forme profiliWebJul 9, 2024 · The purified cDNA (MS-5.1) was characterized by a poly A tail and an open reading frame that encoded 1329 amino acids. The derived amino acid sequence was found to be 99% identical to a 180 kd peripheral endosomal protein named early endosome antigen (EEA1). Results: Antibodies from rabbits immunized with the recombinant … forme profilo